Chili pepper has many nutritional benefits and is widely used as spice among Asian countries. It has also the capability to kill insects found in common households. Keeping in view these facts about Chili pepper and its usability, this study aims to test the efficacy of Chili pepper fruit extract against wood termites. Squeezing method was used to get the juices from the fruit. Fifteen termites were collected from dry wood. They were then placed into three closed containers, sprayed by the extract and observed within 12 hours. Result showed no effects on termites in container A (control group), however, in container B that has 100 percent concentration of the extract, termites were killed abruptly in 5 minutes and after two hours, termites were dead in container C (50 % of chili pepper fruit extract and 50% distilled water). Thus, Fruit extract of chili pepper has positive effects as insecticide against household termites.